https://www.selleckchem.com/pr....oducts/CP-690550.htm
The sample included 38 with iRBD, 205 with PD, and 92 HC who underwent DAT-SPECT at baseline. Over 4.7years of mean follow-up, 14 (36.84%) with iRBD were clinically diagnosed with aSN. Risk of aSN diagnosis was significantly elevated among those with baseline putamen SBR≤48% of that expected for age and sex, relative to those above this cutoff (hazard ratio=17.8 [95%CI 3.79-83.3], P=0.0003). We demonstrate the utility of DAT SBR to identify individuals with iRBD with increased short-term risk of an aSN diagnosis. We demonstrate the ut