https://www.selleckchem.com/products/azd3229.html
Reduced bone mineral density (BMD; ie, Z-score ≤-2. occurring at a young age (ie, premenopausal women and men less then 50 years) in the absence of secondary osteoporosis is considered early-onset osteoporosis (EOOP). Mutations affecting the WNT signaling pathway are of special interest because of their key role in bone mass regulation. Here, we analyzed the effects of relevant LRP5 and LRP6 variants on the clinical phenotype, bone turnover, BMD, and bone microarchitecture. After exclusion of secondary osteoporosis, EOOP patients (n =
Like
Comment
Share
