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≥4 VOCs 47%, = .002) and disease severity (Severity Class II 16% vs. Severity Class III 39%, = .03). There was a weak relationship between VOC frequency and household income (0 VOCs $47,488 vs. ≥4 VOCs $34,569, = .06) and no evidence of a relationship between disease severity class and income (Severity Class II $42,443 vs. Severity Class III $36,842, = .29). In conclusion, disease severity, strongly predicted worse self-reported HRQoL, moderately predicted increased likelihood of collecting disability insurance, and weakly predicted