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The important thing parameters including the adsorbent quantity, sample pH, kind and volume of eluents, type of washing solvents had been evaluated in the removal procedure. Along with ultra-high overall performance liquid chromatography-quadrupole period of flight mass spectrometry (UHPLC-QTOF-MS/MS) evaluation, good linear relationship (1-50 µg·kg-1, R20.9925) and low restrictions of detection (LODs, 0.05-0.56 µg·kg-1) were acquired beneath the optimal conditions.