https://braf-signal.com/epidem....ics-minimization-act
These data indicate underestimation of ADAMTS13 activity because of the made use of fixed assay. In simulated blood supply, two variations, with missense mutations into the area associated with the catalytic domain, displayed only small residual task while all other variants had the ability to successfully digest VWF-platelet complexes. In both assays, considerable proteolytic task could possibly be seen down to 100 ng/ml ADAMTS13. Its thus intriguing to postulate that a lot of alternatives could have sufficien
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