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What Happens If ADHD is Left Untreated in Adults? Untreated ADHD can lead to a range of problems for adults. These include problems with relationships, work and mental health. Adults suffering from untreated ADHD generally have low self-esteem and an unfavorable view of the world. This can cause them to feel as if they are failures at home and work. Lack of Focus It's normal to experience difficulties focusing from time to moment especially after a long day at school or work. However, if you start to notice that your focus has been getting worse and it is affecti