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A new analytical procedure was developed for the determination of lead in human placental tissue by direct ultrasonic slurry sampling combined with electrothermal atomic absorption spectrometry (SS-ET AAS). Samples of dried and crushed placental tissue were mixed with 10 mL of 0.20% (v/v) HNO3 and homogenised. The slurries were then transferred to autosampler cups where they were sonicated using an ultrasonic probe prior to injection into a graphite tube with an L'vov platform. The effects of several chemical modifiers, including Mg(NO3