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The distinctions when you look at the 3-year event-free success and total survival are not statistically considerable. Biosimilar rituximab can suitably and properly change the pioneer rituximab for treatment of diffuse big B cellular lymphoma. © Indian Society of Hematology and Blood Transfusion 2019.Patients with hematological malignancies are seriously immunocompromised consequently they are at risky of invasive fungal infection (IFI), especially those undergoing remission