https://www.selleckchem.com/pr....oducts/acetohydroxam
Specifically, we compare human-induced pluripotent stem cell-derived neurons to directly converted, or transdifferentiated, induced neurons, as both model systems can take advantage of patient-derived human tissue to produce neurons in culture. We present recent technical developments using these two modeling systems, as well as current limitations to these systems, with the aim of advancing investigation of neuropathogenic mechanisms using these models. © 2020 Wiley Periodicals, Inc.This study investigated the effects of l