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Treatment of Add in Adults Treatment of add in adults usually involves a combination of medication, life skills training, and psychotherapy. The majority of patients respond to stimulant medicines such as methylphenidate (Ritalin), and amphetamines such as lisdexamphetamine, (Adderall XR), or extended-release mixed amphetamine salts. The effects of stimulants can raise blood pressure and heart rate. Non-stimulants, like bupropion and atomoxetine, can improve ADHD symptoms. Psychotherapy Psychother