https://www.selleckchem.com/pr....oducts/bms-935177.ht
Histological evaluation of experimental AAA lesions revealed accumulated lipid in neointimal and medial layers, and analysis of human AAA lesions (n=5) obtained from open repair showed medial lipid deposition. In summary, we find that lipid deposition in the aortic wall is a feature of PPE-induced AAA in mice as well as human AAA lesions. Despite, our data do not support the hypothesis that hyperlipidemia contributes to AAA progression. In summary, we find that lipid deposition in the aortic wall is a feature of PPE-induced AAA in mi