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At 4 hours, lactate was re-measured and patients were observed for 28 days then after Lactate clearance was calculated by the following formula ([initial lactate - hour-4 lactate]/initial lactate) × 100. Of the 41 subjects included in the study; 27 died (28-day mortality --65.9%). Age, sex, diagnosis of the patient and Charlson's Comorbidities scores between survivors and non-survivors showed no significant differences. Non-survivors had higher Sequential (sepsis-related) Organ Function Assessment (SOFA) scores (11.41±3.46 versus 8.77±2