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Increased CA125 levels were associated with decreased CD8+ /CD45RA+ /CD45RO- /CCR7- T cells. Conclusion The identified immune clusters serve as the basis for interrogation of the peritoneal immune environment and the development of novel immunologic modalities against ovarian cancer.Objective To investigate the rate and associations of interproximal carious lesion progression. Methods Retrospective data were analysed from 125 young adults (age range 18-29 years) with repeated bitewing radiographs collected over a 6-year period. Participa