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RESULTS MDD patients showed significantly lower DAT BPND in the NAc (p = 0.009), and there was a trend of lower BPND in the putamen (p = 0.032) compared to controls. CONCLUSION We found low DAT in the NAc and putamen in geriatric patients with severe MDD, which could be related to dysregulation of the reward system. This article is protected by copyright. All rights reserved.OBJECTIVE To evaluate the clinical feasibility of NIPD for β-thalassaemia using circulating single molecule amplification and resequencing technology (cSMART). DES