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Polymorphic PTLD was eventually diagnosed. No recurrence or new set lesions were detected after 6-month follow-up. This is the first case describing PTLD may originate from reconstructed MHV after pediatric living donor liver transplant. As a life-threatening complication of liver transplant, surgical resection should be considered as a safe and feasible treatment for the single resectable mass. This is the first case describing PTLD may originate from reconstructed MHV after pediatric living donor liver transplant. As a life-threatening