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RT is an excellent treatment for patients with CIS recurrent after transoral excision and the ones with formerly untreated CIS who tend to be unsuitable for partial laryngectomy.The DNA repair enzyme 8-oxoguanine DNA glycosylase-1 (OGG1) is tangled up in very early embryonic development, as well as in several circumstances, including cardiac fibrosis, diabetes, and neurodegenerative conditions. But, purpose of OGG1 in pulmonary fibrosis wasn't completely obvious. In this research, we