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For example, timosaponin BII, a simple yet effective anti-AD broker, has actually reasonable dental bioavailability. Here, timosaponin BII ended up being developed in a temperature/ion-sensitive in situ hydrogel (ISG) which was really transformed into ties in within the nasal environment. Timosaponin BII safeguarded the PC12 cells hurt by lipopolysaccharides (LPS) by lowering TNF-α and IL-1β and stabilizing F-actin. Timosaponin BII ISGs had been intranasally administer
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