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s and needed to be further confirmed in prospective studies. Hydronephrosis, CT value of hydronephrosis, blood neutrophils, urine leukocyte, and urine culture were independent risk factors to predict pyonephrosis. The novel comprehensive model was found to be an effective method to predict pyonephrosis and needed to be further confirmed in prospective studies.Myocardium functions as an immune organ, and myocardial ischemia-reperfusion (I/R) is known to initiate myocardial innate immune response to induce myocardial injury. However, the mechani