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Here, we examine how MR impacts host immune response to UC plus the effect on immunotherapy response (including checkpoint inhibitors, transformative T mobile therapy, T cell activation, antigen presentation, and changes in the tumor microenvironment). Articles had been identified by literary works online searches on the keywords or recommendations to "UC" and "MR". We discovered a few promising therapeutic methods appearing from preclinical designs that may circumvent suppressive MR results on the d