https://www.selleckchem.com/pr....oducts/17-AAG(Geldan
ALS-FTD participants exhibited variable degrees of apathy (NPI-Q/apathy 1.6 ± 1.2), disinhibition (NPI-Q/disinhibition 1.2 ± 1.2), executive dysfunction (CDR/judgment-problem solving 1.7 ± 0.8). Within the ALS-FTD group, executive dysfunction correlated with dlPFC atrophy (ρ-0.65;p less then 0.05); similar trends were seen for apathy with ACC (ρ-0.53;p less then 0.1 and dmPFC (ρ-0.47;p less then 0.1 atrophy, for disinhibition with OFC atrophy (ρ-0.51;p less then 0.1. Compared to people with ALS, those with ALS