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The mortality and morbidity rate of diabetes patients is increasing worldwide which requires an ideal treatment to prevent the disease worsening. Traditional medicine is gaining more attention in diabetes due to its efficacy and safety. We, therefore performed a systematic review study of clinical trials to assess the comparative effect of polyherbal formulations in type 2 Diabetes mellitus. To find the effectiveness of polyherbal formulations in blood sugar and lipid level for type 2 Diabetes mellitus. PubMed, Scopus and CINAHL databas