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The point estimates of the fixed effects are unbiased for both approaches across all models, as such confirming results from methodological research on IPD meta-analysis of group-comparison designs. #link# In light of these results, we discuss the implementation of both methods in R. To determine the level of quality of life (QoL) in children with cleft lip and/or palate (CL/P) and whether this differs by cleft phenotype. A cohort of children with CL/P born in New Zealand. A nationwide study of children born with CL/P and having primary s