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Our project is to prove feasibility of creation of a clinico-biological database prospectively by collecting epidemiological, socio-economic, clinical, biological, pathological, multi-omic data and to identify characteristics related to the overall survival status before treatment and within 15 years after treatment start from a cohort of 300 patients with a metastatic breast cancer treated in the institution. ClinicalTrials.gov identifier (NCT number) NCT03958136 . Registration 21st of May, 2019; retrospectively registered. ClinicalTr