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ion of the non-paretic eye) and an SVV deviation in the non-paretic eye. The epileptogenicity of recombinant tissue-plasminogen activator (rt-PA) has been suggested, but seizures were not evaluated in randomised controlled trials. To evaluate whether rt-PA was associated with early seizures in a cohort of consecutive patients with cerebral ischaemia. We included consecutive adults with ischaemic stroke due to large-vessel occlusion from the North-of-France stroke network selected for a mechanical thrombectomy (MT). Patient