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Backgrounds and aims To investigate the value of European Deprivation Index (EDI) and Hepatocellular carcinoma (HCC) characteristics and their relationships with outcome after liver transplantation. Methods Patients undergoing liver transplantation (LT) for HCC were included from a national database (from "Agence de la Biomédecine" between 2006 and 2016. Characteristics of the patients were blindly extracted from the Database. Thus, EDI was calculated in 5 quintiles and prognosis factors of survival were determined according to a Cox mod