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Similar stimulatory aftereffects of rPoIL-34 were observed in vivo. When PoIL-34 ended up being overexpressed in flounder, the expressions of pro- and anti-inflammatory mediators had been dramatically affected in a tissue-dependent way, which correlated with an augmented ability of the seafood to eliminate invading pathogens from cells. Collectively, these results suggested that PoIL-34 regulated inflammatory reaction probably vi