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Conclusion Precision dosing through TDM is expanding and it is especially important in communities with altered PK/PD, including critically sick, obese, and older adults. Due to wide PK/PD variability within these populations, TDM is vital to maximize antimicrobial effectiveness and reduce unfavorable event rates. However, there is nonetheless a necessity for scientific studies linking TDM to patient results. Providing patient-specific care through β-lactam TDM and transi