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0053). The analysis also suggested that moderate alcohol consumption (less than 12 drinks in the past 12 months; P for interaction = 0.0003) and maintaining a normal serum glycated hemoglobulin level (HbA1c ≤ 5.7%; P for interaction 0.0001) helped reduce the Pg-related DR risk. The increased Pg-related DR risk could be alleviated by managing alcohol consumption and maintaining a normal blood glucose level. Findings from this study provide new directions for developing novel therapeutics and prevention strategies for DR. Findings f