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The expression of TDRD5 significantly reduced in SCOS, MA and HP specimens than the OA specimens. Indeed, TDRD12 exhibited a very low expression in HP specimens in comparison to OA specimens. All these results were confirmed by Western blot technique. CONCLUSION TDRDs could be very important in male infertility, which should be express in certain stages of spermatogenesis.BACKGROUND Anthrax is an endemic disease that persists in the rural regions of China. The global genetic population structure of B.anthracis has also bee