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We firstly analyzed the plasma Aβ40, Aβ42, and Aβ42/Aβ40 ratio in AD and control team topics. But, only a lower standard of plasma Aβ42 was figured completely in AD group subjects with poor analytical value (WMD 1.82; 95% CI 0.59, 3.06; P = 0.004; I2 = 84%). We considered that the medical records of control topics could influence the biomarker ability of plasma Aβ. Therefore, subgroup analyses had been then performed based on a brand new recruiting criterion for control subjects, determining as no afflicti