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189; 95% confidence interval [CI], 1.122-1.261; P 0.0001). For every 30-day delay in TTS, the hazard of death increased by 4.6%. Subsite analysis showed that the oropharynx subsite was most affected by surgical delays, followed by the oral cavity. Increasing TTS is an independent predictor of survival for patients with HNSCC and should be performed within 67days after diagnosis to achieve optimal survival outcomes. Increasing TTS is an independent predictor of survival for patients with HNSCC and should be performed within 67 days
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