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However, the meta-analysis of RCTs did not confirm these findings. Patient activation can be assessed and addressed uniformly across all chronic conditions to improve patient engagement in care. Patient activation can be assessed and addressed uniformly across all chronic conditions to improve patient engagement in care.Members of class VII cytochromes P450 are catalytically self-sufficient enzymes containing a phthalate dioxygenase reductase-like domain fused to the P450 catalytic domain. Among these, CYP116B46 is the first enzyme for