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Immediately following the intervention, thiamine levels were higher in the thiamine arm (275 vs. 73nmol/L, t-test (df=57)=13.63, p0.0001), but not predictive of delirium. Variables associated with delirium in our sample included disease severity, corticosteroid exposure, infection, and pre-transplantation markers of nutrition. High dose IV thiamine did not prevent delirium in patients receiving allogeneic HSCT. Given the multiple contributors to delirium in this population, further research regarding the efficacy of multicomponent in