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Plasma iFGF23 concentrations in patients with XLH were significantly higher than those in the SF group 146.2 ± 69.2 ng/L vs. 29.5 ± 15.0 ng/L (p 0.001). Remarkably, we did not observe an overlap between XLH and FS patients. Significant hypophosphatemia (2.55 ± 0.50 mg/dL) and secondary hyperparathyroidism (iPTH 109.4 ± 58.1 ng/mL) were present in XLH patients, while FS patients showed modest hypophosphatemia (3.97 ± 0.68 mg/dL), higher TmP/GFR compared with XLH, lower eGFR and hypercalciuria. This study supports the value of measu
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