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The product range of CCR had been bigger in 2021 compared to the many years prior, suggestive of cost shifting by some hospitals to offset the reduction in income. There was a little but considerable boost in white, non-Hispanic patients getting CI in 2020 and 2021, suggestive of a socio-economic move in treatment post pandemic. an organized review of the literature and a meta-analysis were carried out. The CNKI, Wan Fang, PubMed, EMBASE, Cochrane Library, online of Science, and medical tests databases for me