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The initial sort of autophagy plays a role in the loss of cells addressed with drugs. In comparison, the 2nd kind plays a vital role in preventing anticancer drug-induced cell damages; the usage of an autophagy inhibitor is recognized as effective in improving the efficacy of chemotherapy. Hence, it is essential to determine which kind of autophagy is induced during chemotherapy. Right here, we showed that a novel inhibitor of RNA polymerase I, suppresses growth, causes cellular cy