https://www.selleckchem.com/pr....oducts/momordin-ic.h
Quality of warfarin therapy in patients with a mechanical prosthetic heart valve (MPHV) has been barely investigated. We analysed determinants of low time in the therapeutic range (TiTR less then 60%) in 2111 patients with MPHVs from the nationwide PLECTRUM study by the Italian Federation of Anticoagulation Clinics. Overall, 48·5% of patients had a TiTR of less then 60%. At logistic regression analysis, arterial hypertension (odds ratio [OR] 1·502, P less then 0·001), diabetes (OR 1·732, P less then 0·001), heart failure (OR 1·484,