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The results suggest that there is a substitution relationship between informal care and formal home care and that this substitution relationship is stronger for highly impaired middle-aged and older individuals. Our findings will help policy makers understand the complexity of the relationship between informal and formal home care and implement policies accordingly.In 1883, Henri Gourdan de Fromentel defended his thesis on an original topic that has not really been studied since. He examined the simultaneous perception of pain in two d