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nd Dex group when compared with normal group (p0.05). However, it remarkably declined in Dex group in comparison with the model group (p0.05). Finally, ELISA assay indicated that model group and Dex group had markedly higher levels of IL-6 and TNF-α than normal group (p0.05). However, the levels of IL-6 and TNF-α were significantly lower in Dex group than model group (p0.05). Dex inhibits inflammation and apoptosis by suppressing the NF-κB signaling pathway, thereby exerting a protective effect against renal injury in D