https://oicr-9429antagonist.co....m/cross-sectional-bo
Within the studies reported herein, there clearly was no evidence of mutagenicity in a bacterial reverse mutation test or an in vitro mammalian chromosomal aberration test. There was no genotoxic activity seen in an in vivo mammalian micronucleus test at concentrations up to the restriction dose of 2000 mg/kg bw/day. In a 90-day repeated-dose oral poisoning study in HanWIST rats conducted at doses of 0, 500, 1000, and 2000 mg/kg bw/day by gavage, there have been no mort
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