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Next-generation sequencing of patient samples identified a wide array of mutations associated with activated signaling, splicing, and epigenetic modification. In view of the observed low toxicity, a follow-up study combining bisantrene with complementary anti-leukemic therapy is planned. In view of the observed low toxicity, a follow-up study combining bisantrene with complementary anti-leukemic therapy is planned. Previous research suggests that, relative to generating a differential diagnosis, deliberate reflection during practice with