https://www.selleckchem.com/pr....oducts/p5091-p005091
BMI changes from ages 10, 18 to age at mammogram were associated with an increase in BMP2 and decreases in RANK, RANKL, and TNFRSF13B gene expression but were not associated with gene expression of other markers. A 10kg/m increase in early life BMI from age 10 to current age was associated with a 7.8% increase in BMP2 (95% CI=-1.4, 17.8), an 8.5% decrease in RANK (95% CI=-13.9, -2.8), a 10.4% decrease in RANKL (95% CI=-16.9, -3.3), and an 8.5% decrease in TNFRSF13B gene expression (95% CI=-13.8, -2.8). The results provide new insi
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