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In all the references consulted, it has been possible to verify based on the cases detected, positive predictive value and prevalences that the early detection of CH has been highly efficient for the diagnosis of the disease. Neonatal screening for primary CH is an example of success in public health. Lines of research are needed to clarify whether other moderate forms of CH benefit from early detection and treatment. Neonatal screening for primary CH is an example of success in public health. Lines of research are needed to clarify whe