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The latter was supported by comparing it to FTIR results of the modern tissue used.In the process of detecting heterogeneity in breast tissue based on multi-spectral transmission imaging, the detection accuracy will be affected due to the high redundancy degree of information between bands. In order to select the reasonable wavelength combination, this paper uses various nonlinear transformations to convert the multi-spectral images into spectral data for the first time, so as to select the set optimal wavelength combination based on the su