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Female soccer players are particularly susceptible to anterior cruciate ligament (ACL) injuries, accounting for 16% to 43% of the injury burden during the season. Despite the advancements in injury prevention programs, the rate of ACL injuries continues to rise. To provide a comprehensive description of the mechanisms, situational pattern, and biomechanics of ACL injuries in women's soccer. Case series; Level of evidence, 4. We identified 57 consecutive ACL injuries that occurred in matches of 6 top female leagues across 3 s