https://www.selleckchem.com/products/pr-619.html
Use of enteroid models revealed ASM and Ceramide-mediated deleterious mode-of-action when Ceramide reduced the number of intestinal crypt-forming enteroids without affecting their structure, ASM induced a significant decrease of enteroid growth without affecting their number. Identification of specific and different roles for Ceramide and ASM secreted by irradiated endothelial cells opens new perspectives in the understanding of intestinal epithelial dysfunction after radiation and defines a new class of potential therapeutic radiomitiga
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