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CONCLUSIONS In this meta-analysis of 13 randomized studies, low level of proof and significant heterogeneity with tiny sample size limit strong recommendation from the usage of fibrinogen focus in adult surgical patients. But, its use is tolerable without having any significant bad events. TEST REGISTRATION CRD42019149164. Municipal solid waste incineration fly ash (MSWI-FA) is purely managed as hazardous waste globally since it contains different heavy metals a