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ADHD Medications - What Are the Side Effects? Many people suffering from ADHD are prescribed medication. It can improve symptoms, but it can cause adverse negative side effects. Consult your physician if you experience side effects. Stimulants are the most commonly prescribed kind of prescription medication that healthcare providers prescribe for ADHD. These medications increase levels of brain chemicals called neurotransmitters that control the attention span and behavior. Methylphenidate Methylphenidate is a first-choice stimulant used to treat AD