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Here, we utilized mice to characterize the spatial topography and teenage development of cross-corticostriatal (cSTR) neurons that task through the corpus collosum to the dorsomedial striatum. We discovered that apical back density on cSTR neurons into the medial prefrontal cortex decreased dramatically between belated juvenile (P29) and youthful person time points (P6, with females exhibiting higher spine thickness than guys at both ages. Adult males castrated just before puberty on