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Addressing discrepancies in practice could help prioritise professional roles in this area, and better support the management of children with foot pain.BACKGROUND Metastasis and recurrence, wherein circulating tumour cells (CTCs) play an important role, are the leading causes of death in colorectal cancer (CRC). Metastasis-initiating CTCs manage to maintain intravascular survival under anoikis, immune attack, and importantly shear stress; however, the underlying mechanisms remain poorly understood. METHODS In view of the scarcity of C